C—H to C—O Hydroxylations
A preparative small-molecule mimic of liver CYP450 enzymes in the aliphatic C–H oxidation of carbocyclic N-heterocycles
Rachel K. Chambers, Jacob D. Weaver, Jinho Kim, Jason L. Hoar, Shane W. Krska, and M. Christina White
Check out MCW, Rachel and Jake discussing the paper: “Mn(CF3PDP): CYP450 in a Bottle”. https://www.youtube.com/watch?v=ZrV5IPFJc2o
Supplementary Information
Rachel Chambers
Eli Lilly
Jake Weaver
UIUC, White Group
Late-stage oxidative C(sp3)–H methylation
Kaibo Feng, Raundi Quevedo, Jeffrey Kohrt, Martins S. Oderinde, Usa Reilly and M. Christina White
Supplementary Information
Kaibo Feng
MIT, Buchwald Group
Raundi Quevedo
UIUC, White Group
Chemoselective Methylene Oxidation in Aromatic Molecules
Jinpeng Zhao, Takeshi Nanjo, Emilio C. de Lucca Jr. and M. Christina White
Supplementary Information
Takeshi Nanjo
Asst. Professor
Kyoto University
Jinpeng Zhao
Agro Sciences
Corteva
Emilio de Lucca
Asst. Professor
Univ. of Campinas
Remote, Late-Stage Oxidation of Aliphatic C–H Bonds in Amide-Containing Molecules
Takeshi Nanjo, Emilio C. de Lucca Jr.‡ and M. Christina White
Supplementary Information
Takeshi Nanjo
Assistant Professor
Kyoto University
Emilio de Lucca
Assistant Professor
University of Campinas
Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
Thomas J. Osberger, Donald C. Rogness, Jeffery T. Kohrt, Antonia F. Stepan and M. Christina White
Supplementary Information
Thomas Osberger
Assistant Professor,
Cal Poly Pomona
Remote Oxidation of Aliphatic C−H Bonds in Nitrogen-Containing Molecules
Jennifer M. Howell, Kaibo Feng, Joseph R. Clark, Louis J. Trzepkowski, and M. Christina White
Supplementary Information
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Jennifer Howell
Eli-Lilly,
Discovery Chemistry
Joseph Clark
Marquette University
Assistant Professor
Kaibo Feng
MIT,
Buchwald Group
Catalyst-Controlled Aliphatic C–H Oxidations with a Predictive Model for Site-Selectivity
Paul E. Gormisky and M. Christina White
Supplementary Information
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Paul Gormisky
Odyssey Therapeutics
Senior Director
Cafestol to Tricalysiolide B and Oxidized Analogues: Biosynthetic and Derivitization Studies Using Non-heme Iron Catalyst Fe(PDP)
M. A. Bigi, P. Liu, L. Zou, K. N. Houk, and M. C. White
Supplementary Information
Marinus Bigi
Catalysis Discovery,
Dow Chemical
Directed Metal (Oxo) Aliphatic C-H Hydroxylations: Overriding Substrate Bias
M. A. Bigi, S. A. Reed, and M. C. White
Supplementary Information
Marinus Bigi
Catalysis Discovery,
Dow Chemical
Sean Reed
Wilson Sonsini Goodrich & Rosati
Patent Agent
Diverting non-haem iron catalysed aliphatic C—H hydroxylations towards desaturations
M.A. Bigi, S.A. Reed and M.C. White
Supplementary Information
Marinus Bigi
Catalysis Discovery,
Dow Chemical
Sean Reed
Wilson Sonsini Goodrich & Rosati
Patent Agent
Combined Effects on Selectivity in Fe-Catalyzed Methylene Oxidation
M.S. Chen and M.C. White
Supplementary Information
Mark Chen
Lehigh University
Assistant Professor
The Fe(PDP)-catalyzed aliphatic C-H oxidation: a slow addition protocol
N.A. Vermeulen; M.S. Chen; and M.C. White
Nicolaas Vermeulen
Corteva,
Agro Sciences
Mark Chen
Lehigh University
Assistant Professor
A Predictably Selective Aliphatic C-H Oxidation Reaction for Complex Molecule Synthesis
M.S. Chen and M.C. White
Supplementary Information
Mark Chen
Lehigh University
Assistant Professor
